GlobalYeast brings innovation to the industrial fermentation industry by developing and deploying products and solutions while contributing to a more sustainable environment. Established in 2015, GY has pioneered in the development and deployment of advanced digital fermentation solutions. Today we supply clients across the globe. Our unique insight into fermentation processes is based on our industrial know-how from years of experience in the Brazilian ethanol industry and multiple collaborations with yeast and fermentation industries worldwide. Combined with a deep knowledge in process engineering and microbiology, we are well equipped to understand our client’s needs and to deliver tangible results.

 Green Chemicals


Smart Fermentation

BioCal is an advanced solution brought by GlobalYeast that monitors fermentation in real-time. BioCal brings valuable information to plant operation and supervision, translating data into actionable information. This helps the decision-making process in both operational and strategic planning, strengthening industry performance through smart changes.

The monitoring capability of sugar conversion into ethanol unveils information of paramount importance to estimate performance and optimize the process. Therefore BioCal is based on the thorough understanding of cell metabolism and polygenic behavior combined with the evaluation of process inputs.

BioCal® has run under several different settings in Brazilian and US industrial plants.​

These include:​

  • Fed-batch and Continuous processes​
  • Sugarcane, corn starch and 2G hydrolysate as raw materials​
  • Widely varying levels of instrumentation (quality and quantity)​
  • Both standardized and atypical plant layouts​

BioCal® has been able to model all variations in process configuration and has been tailored to each plants’ specific challenges and requests.​

Bringing Industry 4.0 to fermentation

Industrial Yeast Strains

GlobalYeast applies a robust and knowledge-based methodology to the design of superior cell factory yeasts for the production of bio-based fuels and chemicals from various renewable resources.  Leveraging unique insight into fermentation processes through established relationships in the Brazilian and US ethanol industries as well as collaborations with other fermentation-based industries worldwide, GlobalYeast seeks to design tailored strains with superior traits of industrial importance to address customers’ need in terms of robustness and yield.


Excellomol is GlobalYeast’s line of superior yeasts designed specifically for high-gravity cane molasses fermentation. Two strains, XL4 and XL4N have been submitted for consultation in Brazil through the newly defined Normative Resolution #16 for New Breeding Techniques (NBTs) of the National Technical Committee on Biosafety (CTNBio) and became the first industrial yeast strains developed using NBTs to be considered as safe as conventional yeasts by CTNBio. Following this decision, XL4 and XL4N have been made available to pioneer customers to help them address the pressing demands of the Brazilian bioethanol market.

Collaboration Network

COPPE is a highly respected institution in Latin America, known for its important contributions to research and education in many fields of engineering. Boasting thousands of articles published and over a hundred patents filed, it is a reference not only in academia but also with the industry through research agreements and contracts with many of Brazil’s major industry players as well as multinationals. GlobalYeast counts on the expertise and knowledge of one the most academically thriving research groups of this institution for the development of its solutions for the fermentation industry.

Situated in Belgium, in the heart of Western Europe, KU Leuven has been a center of learning for nearly six centuries. Today, it is Belgium’s largest university and, founded in 1425, one of the oldest and most renowned universities in Europe. As a leading European research university and co-founder of the League of European Research Universities (LERU), KU Leuven offers a wide variety of international master’s programs, all supported by high-quality, innovative, interdisciplinary research. KU Leuven is a research-intensive, internationally oriented university that carries out both fundamental and applied research. It is strongly inter- and multidisciplinary in focus and strives for international excellence. To this end, KU Leuven works together actively with its research partners at home and abroad.


GlobalYeast  was formed by an investment consortium of Brazilian and Belgian shareholders.

Vlaams Instituut voor Biotechnologie

VIB is an excellence-based entrepreneurial institute that focuses on translating basic scientific results into pharmaceutical, agricultural and industrial applications. VIB works in close partnership with four universities in Belgium and is funded by the Flemish government. They have backed multiple companies such as Ablynx and Flanders.bio. Their mission is to conduct frontline biomolecular research in life sciences for the benefit of scientific progress and the benefit of society.

Fundo Performa Investimentos

Private Equity and Venture Capital Company focusing investments in the Seed Capital and Growth Capital industries in Brazil. The Company focuses minority investments in the Innovation (Seed Capital) and Middle-Market (Growth Capital) segments of the Brazilian market. Brazilian Sustainable Technology Fund: The Fund is an initiative of the Innovation and Environment Fund Program of BNDES. Investors include: BNDES (Brazilian National Development Bank), SFPI – FPIM (The Federal Holding and Investment Company of Belgium), AgeRio (Rio de Janeiro Estate Development Agency) and 3 family offices.

Gemma Frisius Fund – KU Leuven

GFF is a seed capital fund, established in 1997 as a joint venture between KU Leuven, the KBC Group and the BNP Paribas Group. The objective of the fund is to stimulate the creation and growth of KU Leuven related spin-off companies. As an evergreen fund, GFF acts as a long term shareholder and partner to the companies it has provided funds to.

Participatiemaatschappij Vlaanderen

PMV NV is an independent investment company. PMV collaborates with private partners via funds and public-private partnerships. Particular emphasis is placed on sustainable energy, biotech, cleantech, life sciences and infrastructure for the future. SOFI-fund: PMV is investing in incubation projects and spin-off companies from the four strategic research centers in Flanders.